A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it. (Pixabay)

B.C. biotech firm seeks emergency approval for COVID-killing nasal spray

Clinical trials found SaNOtize reduces virus levels in upper airways by more than 99%, developers say

A B.C. biotech firm is seeking federal approval for the emergency use of a nasal spray, claiming it significantly lessens the impact and severity of COVID-19 for those who use it.

The Vancouver start-up said clinical trials found SaNOtize reduced coronavirus levels in participants’ upper airways by 95 per cent in one day and more than 99 per cent in three.

The portable treatment expels a nitric oxide solution, “halt(ing) viral replication within the nasal cavity, which rapidly reduces viral load,” said Dr. Chris Miller, chief science officer and co-founder.

“This is significant because viral load has been linked to infectivity and poor outcomes,” Miller said.

During months of testing, COVID-19 patients in Canada and the U.K. self-administered the nasal spray. When treated quickly enough, the virus was eliminated before it spread to the lungs.

SaNOtize also proved effective against COVID-19 variant B117, which originated in the U.K.

READ MORE: B.C. researchers generating COVID-19 breath test that could give results in 1 minute

None of the participants reported adverse side effects during trials.

If approved for use, SaNOtize could help those with COVID-19 experience milder symptoms and potentially recover quicker from the disease, according to Miller.

“We must move with urgency to get it into the hands of the public where it can help bring an end to the pandemic and prevent future outbreaks of COVID-19 and its variants,” said Dr. Gilly Regev, CEO and co-founder.

The developers are hoping the nasal spray can be used internationally, as a form of protection against COVID-19, similar to that of hand sanitizer.

The biotech company is planning clinical trials to prove SaNOtize can prevent COVID-19 transmission in humans. The product is expected to cost $50 per bottle if it makes its way to consumers.

RELATED: Vancouver biotech company discovering antibodies for COVID-19 treatment



sarah.grochowski@bpdigital.ca

Like us on Facebook and follow us on Twitter.

Want to support local journalism? Make a donation here.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Tala MacDonald, a 17-year-old student at Mount Sentinel Secondary who is also a volunteer firefighter, has won the $100,000 Loran Scholarship. Photo: Submitted
West Kootenay student wins $100K scholarship

Tala MacDonald is one of 30 Canadians to receive the Loran Scholarship

Elvira D’Angelo, 92, waits to receive her COVID-19 vaccination shot at a clinic in Montreal, Sunday, March 7, 2021, as the COVID-19 pandemic continues in Canada and around the world. THE CANADIAN PRESS/Graham Hughes
110 new cases of COVID-19 in Interior Health

Provincial health officers announced 1,005 new cases throughout B.C.

Kristian Camero and Jessica Wood, seen here, co-own The Black Cauldron with Stephen Barton. The new Nelson restaurant opened earlier this month while indoor dining is restricted by the province. Photo: Tyler Harper
A restaurant opens in Nelson, and no one is allowed inside

The Black Cauldron opened while indoor dining is restricted in B.C.

These two city-owned houses on Railway Avenue in the Railtown district will be sold. Photo: Bill Metcalfe
City of Nelson will sell two derelict houses in Railtown

Purchasers will be responsible for demolition and slope stability issues

Vancouver resident Beryl Pye was witness to a “concerning,” spontaneous dance party that spread throughout social groups at Kitsilano Beach on April 16. (Screen grab/Beryl Pye)
VIDEO: Dance party erupts at Vancouver’s Kitsilano Beach to the dismay of onlookers

‘It was a complete disregard for current COVID-19 public health orders,’ says Vancouver resident Beryl Pye

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

A syringe is loaded with COVID-19 vaccine at a vaccination clinic run by Vancouver Coastal Health, in Richmond, B.C., Saturday, April 10, 2021. THE CANADIAN PRESS/Jonathan Hayward
B.C. to open up COVID vaccine registration to all B.C. residents 18+ in April

Registration does not equate to being able to book an appointment

(Black Press file photo).
Multiple stabbings at Vancouver Island bush party

Three youths hospitalized after an assault in Comox

Selina Robinson is shown in Coquitlam, B.C., on Friday November 17, 2017. British Columbia’s finance minister says her professional training as a family therapist helped her develop the New Democrat government’s first budget during the COVID-19 pandemic, which she will table Tuesday. THE CANADIAN PRESS/Darryl Dyck
B.C. finance minister to table historic pandemic-challenged deficit budget

Budget aims to take care of people during pandemic while preparing for post-COVID-19 recovery, Robinson said

Each spring, the Okanagan Fest-of-Ale is held in Penticton. This year, as a result of the COVID-19 pandemic, the festival will not be held. However, beer is still available. How much do you know about this beverage? (pxfuel.com)
QUIZ: How much do you really know about beer?

Put your knowledge to the test with this short quiz

Lord Tweedsmuir’s Tremmel States-Jones jumps a player and the goal line to score a touchdown against the Kelowna Owls in 2019. The face of high school football, along with a majority of other high school sports, could significantly change if a new governance proposal is passed at the B.C. School Sports AGM May 1. (Malin Jordan)
Power struggle: New governance model proposed for B.C. high school sports

Most commissions are against the new model, but B.C. School Sports (BCSS) and its board is in favour

Pall Bearers carrying the coffin of the Duke of Edinburgh, followed by the Prince of Wales, left and Princess Anne, right, into St George’s Chapel for his funeral, at Windsor Castle, in Windsor, England, Saturday April 17, 2021. (Danny Lawson/Pool via AP)
Trudeau announces $200K donation to Duke of Edinburgh award as Prince Philip laid to rest

A tribute to the late prince’s ‘remarkable life and his selfless service,’ the Prime Minister said Saturday

B.C. homeowners are being urged to take steps to prepare for the possibility of a flood by moving equipment and other assets to higher ground. (J.R. Rardon)
‘Entire province faces risk’: B.C. citizens urged to prepare for above-average spring flooding

Larger-than-normal melting snowpack poses a threat to the province as warmer weather touches down

Most Read