A person wearing a face mask to curb the spread of COVID-19 is silhouetted against B.C. Place stadium while walking over a pedestrian bridge on False Creek, in Vancouver, on Friday, April 2, 2021. THE CANADIAN PRESS/Darryl Dyck

A person wearing a face mask to curb the spread of COVID-19 is silhouetted against B.C. Place stadium while walking over a pedestrian bridge on False Creek, in Vancouver, on Friday, April 2, 2021. THE CANADIAN PRESS/Darryl Dyck

Experts say COVID variants likely make up 40% of B.C.’s cases, double what officials have disclosed

The B.1.1.7 variant alone makes up a third of B.C.’s cases. It’s expected to reach 60%, catching up with Ontario in about a month.

British Columbia is severely under-reporting the number of COVID-19 cases that are variants of concern, limiting the public’s awareness of the threat, experts say.

Sarah Otto, a University of British Columbia professor who has done COVID-19 modelling, said the province’s reliance on time-consuming whole-genome sequencing to confirm variant cases is not necessary.

She said the PCR test used to identify all COVID-19 cases in the province already detects a mutation that the three major variants of concern have in common. B.C. could also adopt a newer method to distinguish between the variants as part of the test, she added.

Instead, the province only reports cases once they’ve been confirmed through whole-genome sequencing. Otto said she doesn’t believe B.C. has the capacity to sequence all presumptive variant cases identified by the PCR test, and is under-reporting them as a result.

Sharing timely, complete information about these more-transmissible variants would help enlist more B.C. residents in the “concerted effort” needed to curb the spread, Otto said.

“If a patient comes into the hospital and knows it’s a variant, then you already know the person is at basically double the risk, and so doctors should be treating the cases more cautiously,” she said.

“As well, if you just got it and you realize you’re carrying a variant, people may just be that much more cautious in the way that we want.”

B.C. has reported 3,766 cases that are variants of concern to date, including 2,837 of the B.1.1.7 variant first identified in the United Kingdom, 51 of the B. 1.351 strain first detected in South Africa and 878 of the P. 1 variant first found in Brazil.

Provincial health officer Dr. Bonnie Henry said Tuesday that 266 variant cases are active, just three per cent of overall active cases.

However, in the same briefing, she also said the B.1.1.7 variant makes up a third of B.C.’s cases and she expects it to reach 60 per cent, catching up with Ontario, in about a month.

Jens von Bergmann, a mathematician who does data analysis, said the three per cent figure is a “meaningless” number. The province is not sequencing all variant cases, and for those it does sequence, they are likely no longer active by the time the work is done, he said.

He said B.1.1.7 making up a third of B.C.’s infections sounds more accurate, although he suspected that data was a week or two old. Both he and Otto believe variant cases represent about 50 per cent of current infections in the province.

A preprint paper done by BC Centre for Disease Control scientists shows that publicly reported figures of variants of concern are lower than those captured by the PCR test.

The paper, recently posted on a public server ahead of formal peer review, says that 23 presumptive variant cases were identified by the PCR test the week of Jan. 31, representing just over one per cent of infections.

For the week of Feb. 28, there were 434 presumptive variant cases, or 12.2 per cent of infections, the paper says.

The authors of the paper concluded that there was a “high concordance” between PCR testing and whole-genome sequencing, and that a combined testing approach was feasible.

The BC Centre for Disease Control did not immediately respond to requests for comment.

In contrast with the figures in the paper, Henry and Health Minister Adrian Dix reported that the province had only seen 14 variant cases by the end of January, with that number growing to 158 by the end of February.

On March 25, Henry said the percentage of variant cases was in the “high teens” to “early 20s.”

Otto and von Bergmann both said that given the exponential growth of variants of concern, it’s likely that they now account for about half of active cases.

Henry said Tuesday the province screens about 90 per cent of positive tests for the mutation associated with the three major variants of concern. All of the samples that contain the mutation undergo whole-genome sequencing, she said.

Otto said she believed that Henry’s remarks were based on outdated information.

“I know that they intended to sequence everything that had come up as a variant. That was possible when it was just a few cases or a few hundred cases. But we’re getting into the region where it’s a few thousand cases a week,” she said.

Ontario reports daily on the variant cases identified by PCR testing. It is able to detect cases involving B.1.1.7 based on the test alone, but must do whole-genome sequencing to distinguish between P. 1 and B. 1.351.

Henry said reporting variants of concern based on the PCR test would provide an “inflated” figure because other variants also contain the mutation that the three major ones share.

But von Bergmann noted that the BC Centre for Disease Control paper showed that one out of 23 presumptive variants of concern identified by the PCR test was found to be a non-variant of concern following whole-genome sequencing.

At the same time, he pointed out, another one of those 23 could not undergo sequencing because there wasn’t enough genetic material.

“It cuts both ways and we are giving an extremely deflated count right now.”

Coronavirus

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

A mushroom grower plans to plan new mushrooms in fallen trees in the Kaslo Community Forest. File photo
Kaslo mushroom farmer given green light for unique project

Robin Mercy will plant mushrooms in the Kaslo Community Forest

Nelson dancers Glynis Waring, Slava Doval and Amanda Papailhou, and musician Nella Banner, premier Respired on April 11. Photo: Submitted
New dance work the latest online offering from Capitol Theatre

Local performers will unveil Respired beginning April 11

B.C's COVID-19 dashboard shows the peaks and valleys of cases prior to the record daily report of 132 on April 9, 2021. (Dashboard image)
Interior Health has record day of COVID-19 cases

132 cases reported Friday, April 9, more deaths in Vernon hospital outbreak

B.C. Health Minister Adrian Dix and Premier John Horgan describe vaccine rollout at the legislature, March 29, 2021. (B.C. government)
1,262 more COVID-19 infections in B.C. Friday, 9,574 active cases

Province’s mass vaccination reaches one million people

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

People walk past the Olympic rings in Whistler, B.C., Friday, May 15, 2020. Whistler which is a travel destination for tourists around the world is seeing the effects of travel bans due to COVID-19. THE CANADIAN PRESS/Jonathan Hayward
Adults living, working in Whistler, B.C., eligible for COVID-19 vaccine on Monday

The move comes as the province deals with a rush of COVID-19 and variant cases in the community

RCMP crest. (Black Press Media files)
UPDATE: RCMP investigating after child, 6, dies at motel in Duncan, B.C.

The BC Coroners Service is conducting its own investigation into the circumstances around the child’s death

RCMP display some of the fish seized from three suspects who pleaded guilty to violating the Fisheries Act in 2019, in this undated handout photo. THE CANADIAN PRESS/HO - RCMP
3 banned from fishing, holding licences after overfishing violations near Vancouver Island

Mounties seized the group’s 30-foot fishing vessel and all equipment on board at the time

B.C. Premier John Horgan responds to questions during a postelection news conference in Vancouver, on Sunday, October 25, 2020. British Columbia’s opposition Liberals and Greens acknowledge the COVID-19 pandemic has presented huge challenges for Horgan’s government, but they say Monday’s throne speech must outline a coherent plan for the province’s economic, health, social and environmental future. THE CANADIAN PRESS/Darryl Dyck
Horgan’s NDP to bring in throne speech in B.C., Opposition wants coherent plan

Farnworth said the budget will include details of government investment in communities and infrastructure

FILE - An arena worker removes the net from the ice after the Vancouver Canucks and Calgary Flames NHL hockey game was postponed due to a positive COVID-19 test result, in Vancouver, British Columbia, in this Wednesday, March 31, 2021, file photo. As vaccinations ramp up past a pace of 3 million a day in the U.S, the NHL is in a tougher spot than the other three major North American professional sports leagues because seven of 31 teams are based on Canada. (Darryl Dyck/The Canadian Press via AP, File)
Vancouver Canucks scheduled to practice Sunday, resume games April 16 after COVID outbreak

Canucks outbreak delayed the team’s season by eight games

Most Read