According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

According to an analysis by the federal Centers for Disease Control and Prevention published Tuesday (April 6) most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows. (NIAID-RML via AP, File)

Most kids with serious inflammatory illness had mild COVID-19

The post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half received intensive hospital care

Most children with a serious inflammatory illness linked to the coronavirus had initial COVID-19 infections with no symptoms or only mild ones, new U.S. research shows.

The unusual post-infection condition tends to be milder in kids who were sicker with COVID-19, although more than half of affected youngsters received intensive hospital care, according to an analysis by the federal Centers for Disease Control and Prevention published Tuesday in JAMA Pediatrics.

The study represents the largest analysis to date on U.S. cases of multisystem inflammatory syndrome in children and bolsters evidence that it is a delayed immune response to COVID-19. The study included almost 1,800 cases reported to the CDC from March 2020 through mid-January. Most were in kids younger than 15 but the study included up to age 20.

Upticks in cases have occurred two to five weeks after COVID-19 peaks and have followed spread of initial infections from urban to rural areas, the researchers said. More recent CDC data indicate there’s another emerging peak in the pediatric condition consistent with that trend.

State-reported cases through March 29 totalled 3,185 and included 36 deaths, the CDC’s website shows. State reports aren’t always timely so it is uncertain how many U.S. children developed the illness since the study ended.

Most kids who had COVID-19 don’t develop post-infection illness. Almost 3.5 million U.S. children and teens have tested positive for COVID-19, according to data compiled by the American Academy of Pediatrics and the Children’s Hospital Association.

The condition was first reported in Europe in late winter and spring of last year. Some cases, especially those that follow silent, undiagnosed COVID-19 infections, may be mistaken for Kawasaki disease, a rare condition that can cause red skin, swelling and heart problems.

Dr. Sean O’Leary, vice chairman of the pediatrics academy’s infectious diseases committee, said the inflammatory condition typically causes children to become very sick very quickly, but that most ‘’respond very well to treatment and the vast majority get completely better.’’

Treatments may include steroids and other medicines that can reduce inflammation.

The best way to prevent it is to prevent COVID-19 infections, ‘’which vaccines are very good at doing,’’ he said. COVID-19 vaccine studies in children are underway.

In the CDC analysis, fever was among the most common symptoms. Abdominal pain, vomiting, diarrhea and red skin rash occurred in at least half of affected kids. Almost one-third had heart inflammation or other cardiac involvement. These symptoms were least common among children up to age 4, who were also less likely to require intensive care than older children.

CoronavirusHealth

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Tala MacDonald, a 17-year-old student at Mount Sentinel Secondary who is also a volunteer firefighter, has won the $100,000 Loran Scholarship. Photo: Submitted
West Kootenay student wins $100K scholarship

Tala MacDonald is one of 30 Canadians to receive the Loran Scholarship

Elvira D’Angelo, 92, waits to receive her COVID-19 vaccination shot at a clinic in Montreal, Sunday, March 7, 2021, as the COVID-19 pandemic continues in Canada and around the world. THE CANADIAN PRESS/Graham Hughes
110 new cases of COVID-19 in Interior Health

Provincial health officers announced 1,005 new cases throughout B.C.

Kristian Camero and Jessica Wood, seen here, co-own The Black Cauldron with Stephen Barton. The new Nelson restaurant opened earlier this month while indoor dining is restricted by the province. Photo: Tyler Harper
A restaurant opens in Nelson, and no one is allowed inside

The Black Cauldron opened while indoor dining is restricted in B.C.

These two city-owned houses on Railway Avenue in the Railtown district will be sold. Photo: Bill Metcalfe
City of Nelson will sell two derelict houses in Railtown

Purchasers will be responsible for demolition and slope stability issues

Vancouver resident Beryl Pye was witness to a “concerning,” spontaneous dance party that spread throughout social groups at Kitsilano Beach on April 16. (Screen grab/Beryl Pye)
VIDEO: Dance party erupts at Vancouver’s Kitsilano Beach to the dismay of onlookers

‘It was a complete disregard for current COVID-19 public health orders,’ says Vancouver resident Beryl Pye

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

A syringe is loaded with COVID-19 vaccine at a vaccination clinic run by Vancouver Coastal Health, in Richmond, B.C., Saturday, April 10, 2021. THE CANADIAN PRESS/Jonathan Hayward
B.C. to open up COVID vaccine registration to all B.C. residents 18+ in April

Registration does not equate to being able to book an appointment

(Black Press file photo).
Multiple stabbings at Vancouver Island bush party

Three youths hospitalized after an assault in Comox

Selina Robinson is shown in Coquitlam, B.C., on Friday November 17, 2017. British Columbia’s finance minister says her professional training as a family therapist helped her develop the New Democrat government’s first budget during the COVID-19 pandemic, which she will table Tuesday. THE CANADIAN PRESS/Darryl Dyck
B.C. finance minister to table historic pandemic-challenged deficit budget

Budget aims to take care of people during pandemic while preparing for post-COVID-19 recovery, Robinson said

Each spring, the Okanagan Fest-of-Ale is held in Penticton. This year, as a result of the COVID-19 pandemic, the festival will not be held. However, beer is still available. How much do you know about this beverage? (pxfuel.com)
QUIZ: How much do you really know about beer?

Put your knowledge to the test with this short quiz

Lord Tweedsmuir’s Tremmel States-Jones jumps a player and the goal line to score a touchdown against the Kelowna Owls in 2019. The face of high school football, along with a majority of other high school sports, could significantly change if a new governance proposal is passed at the B.C. School Sports AGM May 1. (Malin Jordan)
Power struggle: New governance model proposed for B.C. high school sports

Most commissions are against the new model, but B.C. School Sports (BCSS) and its board is in favour

Pall Bearers carrying the coffin of the Duke of Edinburgh, followed by the Prince of Wales, left and Princess Anne, right, into St George’s Chapel for his funeral, at Windsor Castle, in Windsor, England, Saturday April 17, 2021. (Danny Lawson/Pool via AP)
Trudeau announces $200K donation to Duke of Edinburgh award as Prince Philip laid to rest

A tribute to the late prince’s ‘remarkable life and his selfless service,’ the Prime Minister said Saturday

B.C. homeowners are being urged to take steps to prepare for the possibility of a flood by moving equipment and other assets to higher ground. (J.R. Rardon)
‘Entire province faces risk’: B.C. citizens urged to prepare for above-average spring flooding

Larger-than-normal melting snowpack poses a threat to the province as warmer weather touches down

Most Read